Why Does Lithium Help Bipolar Disorder?

1 025 Shikime 103 mijë

There’s no doubt that lithium has a diverse list of uses. But the way that it interacts with our bodies to help treat bipolar disorder is aiding us in better understanding the disorder and potentially developing new drugs to combat it.

Hosted by: Brit Garner
----------
Support SciShow by becoming a patron on Patreon: www.patreon.com/scishow
SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at www.scishowtangents.org
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Silas Emrys, Charles Copley, Drew Hart, Jeffrey Mckishen, James Knight, Christoph Schwanke, Jacob, Matt Curls, Christopher R Boucher, Eric Jensen, Lehel Kovacs, Adam Brainard, Greg, GrowingViolet, Ash, Laura Sanborn, Sam Lutfi, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, charles george, Alex Hackman, Chris Peters, Kevin Bealer
----------
Looking for SciShow elsewhere on the internet?
Facebook: scishow
Twitter: scishow
Tumblr: scishow.tumblr.com
Instagram: thescishow
----------
Sources:
www.rsc.org/periodic-table/element/3/lithium
link.springer.com/article/10.1007/s11837-013-0666-4
www.rsc.org/periodic-table/element/3/lithium
dictionary.cambridge.org/us/pronunciation/english/carbonate
apps.who.int/iris/bitstream/handle/10665/325771/WHO-MVP-EMP-IAU-2019.06-eng.pdf?ua=1
www.sciencedaily.com/releases/2017/03/170320143837.htm
www.ncbi.nlm.nih.gov/pmc/articles/PMC1238187/pdf/westjmed00262-0038.pdf
www.eurekalert.org/pub_releases/2017-05/spmd-umm050517.php
www.ncbi.nlm.nih.gov/pmc/articles/PMC3712976/
www.popularmechanics.com/technology/gadgets/g1096/a-brief-history-of-the-lightbulb/?slide=2
journalbipolardisorders.springeropen.com/articles/10.1186/s40345-019-0151-2
www.mayoclinic.org/diseases-conditions/bipolar-disorder/symptoms-causes/syc-20355955
www.ncbi.nlm.nih.gov/pmc/articles/PMC1238187/pdf/westjmed00262-0038.pdf
www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Psychiatry_Guide/787045/all/Bipolar_I_Disorder
www.who.int/medicines/publications/essentialmedicines/en/
onlinelibrary.wiley.com/doi/abs/10.1111/bdi.12423
www.ncbi.nlm.nih.gov/pmc/articles/PMC6723289/
www.mayoclinic.org/diseases-conditions/bipolar-disorder/symptoms-causes/syc-20355955
www.google.com/books/edition/_/W-UWDgAAQBAJ?hl=en&gbpv=1&bsq=gonda
www.ncbi.nlm.nih.gov/pmc/articles/PMC3669924/
www.pnas.org/content/114/22/E4462
www.ncbi.nlm.nih.gov/pmc/articles/PMC4063501/
journals.sagepub.com/doi/pdf/10.1177/2040622311399173
www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61828-6/fulltext
journalbipolardisorders.springeropen.com/articles/10.1186/s40345-014-0014-9
www.ncbi.nlm.nih.gov/pmc/articles/PMC4414735/
www.nist.gov/news-events/news/2016/07/new-model-may-help-solve-mystery-how-lithium-stabilizes-moods
www.cell.com/biophysj/fulltext/S0006-3495(16)30461-1
www.ncbi.nlm.nih.gov/pmc/articles/PMC4312318/
www.frontiersin.org/articles/10.3389/fnmol.2018.00349/full
www.ncbi.nlm.nih.gov/pmc/articles/PMC6024559/
www.pnas.org/content/114/22/E4462
pubmed.ncbi.nlm.nih.gov/11137153/
www.nbcnews.com/health/mental-health/why-does-it-take-so-long-diagnose-bipolar-disorder-n865171
pubs.rsc.org/en/content/articlelanding/2018/SC/c7sc05284g#!divAbstract
www.chemistryworld.com/news/new-theory-for-why-lithium-helps-bipolar-patients/3008926.article
www.nature.com/scitable/topicpage/gpcr-14047471/
www.britannica.com/science/G-protein-coupled-receptor
www.khanacademy.org/science/ap-biology/cell-communication-and-cell-cycle/changes-in-signal-transduction-pathways/v/g-protein-coupled-receptors
www.webmd.com/vitamins/ai/ingredientmono-1065/lithium
www.ncbi.nlm.nih.gov/books/NBK507255/
www.ncbi.nlm.nih.gov/books/NBK21718/
www.istockphoto.com/photo/periodic-table-lithium-gm470802481-35227142
www.istockphoto.com/vector/realistic-vector-smartphone-illustration-gm1141533939-305872261
www.istockphoto.com/vector/isometric-gm1149826915-311038438
www.istockphoto.com/vector/heart-icon-with-a-cardio-line-vector-illustration-gm1266963099-371567662
www.istockphoto.com/photo/doctor-medical-and-healthcare-concept-gm964796800-263350087
www.istockphoto.com/photo/paintography-double-exposure-close-up-of-an-attractive-model-combined-with-hand-gm1188220829-335943587
www.storyblocks.com/video/stock/inside-the-brain-neurotransmitter-neuron-network-firing-electro-chemical-signals-bbha2u7ovkgposseq
www.storyblocks.com/video/stock/doctor-in-white-coat-meeting-with-female-patient-shot-on-r3d-hm33km5teizg0i7hh

Komente

  1. Star Burst
    Star Burst
    Ditë më parë

    I got the medicine but I’m scared to take it because of the side effects

    1. Mervyn Ronald
      Mervyn Ronald
      8 orë më parë

      Same I just got my medicine too

  2. John Talmage
    John Talmage
    5 ditë më parë

    "If it's surprising that the same element used in batteries, would be good for the brain" To be sure, lithium is toxic, and bipolar patients who are treated with it are closely monitored thru blood testing...... Please try to remember that we live in a lunatic culture where someone could hear your words, and think of ingesting or injecting their cell phone battery. Taking lithium may be necessary for some....but the use of the word "good" wasn't necessary to convey the point, and created edutainment with risk of harm as it's potential cost.

  3. Zul Azlan
    Zul Azlan
    6 ditë më parë

    Lithium carbonate has narrow theraputic and toxic range, and its concentration easily changes according to the body's hydration status. thryoid function test, serum amylase and blood urea & creatinine test have to be performed regularly as lithium is toxic to thyroid, pancreas and also kidneys

  4. Boston Bob
    Boston Bob
    8 ditë më parë

    I can't take lithium because only have one kidney it can damage the kidneys

  5. Sad Alien
    Sad Alien
    10 ditë më parë

    My dad took lithium for Bipolar 2 for at least 15 years. After a while, it gets less and less useful and eventually he had to change meds. It worked great while he used it though.

  6. TcFW97TCM
    TcFW97TCM
    14 ditë më parë

    They diagnosed me with bipolar in two years and I think it was wrong. Well no meds for me , and I think I'm doing alright

  7. Jacky B
    Jacky B
    15 ditë më parë

    Vera veltri we know what you are!!!

  8. Altitude Fishing
    Altitude Fishing
    19 ditë më parë

    I identify as a senior citizen. My birth year was 1999 but I've always felt like a 76 old man deep inside and in my knees and back haha. I've always felt like I was born on 03/25/1945 which is my birthday i felt I was born in. I Finally came out todays as a senior citizen praise Jesus chrioooostt 🙌❤❤❤🖕😏😳 I see my age only as a spectrum 🖕🤣🤣🤣🤣🥳🥳😎🦳🧓👵👴 I just turn 76 last month I feel to happy to come out and say to the world that I'm a 76 year old Mexican straight man with no grandchildren 😔😭😭😭

  9. vvMathematicalvv
    vvMathematicalvv
    20 ditë më parë

    I did Biochemistry research as an undergrad on this. Ran and managed many experiments. Fascinating biochemistry.

  10. Robin Hooper
    Robin Hooper
    20 ditë më parë

    I was diagnosed with depression and medication to treat that for many years. Overtime I figured out that I don't have depression but seasonal bipolar disorder. Thank You for the Lithium heads up.

  11. EXLOVE
    EXLOVE
    20 ditë më parë

    I just wish there was a clear cut cure for this. I hate feeling these feelings man

  12. JERRY MATHEW
    JERRY MATHEW
    21 ditë më parë

    Great shape😘😘

  13. The Light
    The Light
    21 ditë më parë

    I wish you would have gone into greater detail on why bipolar people can expect 9-17 years shaved off of their lives.

  14. piecesofme
    piecesofme
    22 ditë më parë

    They just needed to recharge their batteries.

  15. Mr. Bloom
    Mr. Bloom
    22 ditë më parë

    I take Lithium Carbonate have been for a while it works for me so yay.

  16. FlyOnTheWall
    FlyOnTheWall
    23 ditë më parë

    Lithium didn't help me. Bupropian (wellbutrin) did a much better job for me. That's before I lost my job due to lockdown and could afford medication.

  17. oceans taiga
    oceans taiga
    24 ditë më parë

    *starts unpacking batteries and chewing on them*

  18. Spyrit2011
    Spyrit2011
    25 ditë më parë

    Why not start with dietary needs, carnivore to reset the body and keto to sustain it?

  19. Alexandre Poirier
    Alexandre Poirier
    25 ditë më parë

    use LSD is works. i know someone taking lithium and instead with Lsd Micro dosing its better to the same

  20. MARS
    MARS
    26 ditë më parë

    Insert Evanescence song "Lithium" here:

  21. Bill Farrell
    Bill Farrell
    28 ditë më parë

    Ruh Roh, bipolar shortens your life expectancy by 5-17 years? How depressing, I had no idea.

  22. Brad Foster
    Brad Foster
    29 ditë më parë

    Anything they did for mental health in the 1800's can f right off. Chemical Lobotomy.

  23. Grace
    Grace
    Muaj më parë

    I like her! Great video

  24. Josh Posh
    Josh Posh
    Muaj më parë

    Makes you wonder how much mental illness is just bad diet.

  25. Ryn !
    Ryn !
    Muaj më parë

    ..hmm I was put on lithium for major depressive disorder but now that I think about it, my symptoms are kind of reminiscent of bipolar disorder. I wonder if there’s something my doctor isn’t telling me..

  26. BibiBosh
    BibiBosh
    Muaj më parë

    I had a dream last night that I was playing with Lead. I remembered that lead is bad for you , i looked at my hands . They were covered in black. It was a nightmare because I thought id get lead poisoning. So I stopped playing with the ball of lead and woke up .

  27. neomt2
    neomt2
    Muaj më parë

    I thought lithium is for heart attacks,?

  28. Stephen Schneider
    Stephen Schneider
    Muaj më parë

    Does work but significant toxicities, try depakote first

  29. Matt Horrocks
    Matt Horrocks
    Muaj më parë

    Dont take lithium you WILL gain 20% body fat. Look it up.

    1. Matthew McGraw
      Matthew McGraw
      27 ditë më parë

      Lithium orotate is safe, lithium carbonate is not safe do some research Lithium orotate is super low dose and changed my life for the better because its super absorbable at very low milligrams while lithium carbonate is high dose and toxic because of it

  30. N33T0 K1M
    N33T0 K1M
    Muaj më parë

    No

  31. Prospect
    Prospect
    Muaj më parë

    It's not good it just ruins access to instincts (limbic systems) high mesolimbic dopamine cause it's a poison...

    1. Matthew McGraw
      Matthew McGraw
      27 ditë më parë

      Lithium orotate is the way to go is on Amazon

  32. Jack Ames
    Jack Ames
    Muaj më parë

    great video

  33. Jack Capricorn
    Jack Capricorn
    Muaj më parë

    I wish Sci Show wouldn’t edit out natural pauses between sentences... it’s better for our brains to have a little _space_ to integrate information.

    1. Chandelier C
      Chandelier C
      14 ditë më parë

      I second this request...

  34. fancydeer
    fancydeer
    Muaj më parë

    Huh I had to stop taking lithium because it made me thirsty. like UNGODLY levels of thirsty. I was never not thirsty the entire time I was on lithium. I couldn't stand it anymore. I finally got my meds figured out after about 4 or so years of trying stuff. Lithium worked for me but I couldn't handle all the side effects.

  35. Cdb Cdb
    Cdb Cdb
    Muaj më parë

    I mean this with all due respect in the world: the host reminds me of Pam from Archer.

  36. robert barraza
    robert barraza
    Muaj më parë

    Why do psychic medicine always sound scary and side effects make u wonder if u should take them at all.

  37. I never look at replies lol
    I never look at replies lol
    Muaj më parë

    I dunno...same reason alcohol helps alcoholics?

  38. E V
    E V
    Muaj më parë

    That woman in the video seems to have hypothyroidism.

  39. Roedy Green
    Roedy Green
    Muaj më parë

    One problem with lithium is you need a high dose to get an effect. This is dangerously close to a fatal dose, You must be very careful not to double dose,

  40. Pablo David Clavijo
    Pablo David Clavijo
    Muaj më parë

    Is it a coincidence that lithium is used in batteries, which are also bipolar? Probably yes

  41. sambhav jain
    sambhav jain
    Muaj më parë

    Nirvana

  42. Smizoke Mizark
    Smizoke Mizark
    Muaj më parë

    I use it to treat depression and it works great

    1. Matthew McGraw
      Matthew McGraw
      27 ditë më parë

      Lithium orotate is better and its safe, lithium carbonate is toxic and poorly a absorbed. Also lithium orotate is available on Amazon no prescription needed

  43. Alexis McCrory
    Alexis McCrory
    Muaj më parë

    I'd really appreciate if you could make a video going over the spectrum of psychotic disorders! (schizophrenia to bipolar - bipolar with psychotic features and schizoaffective disorder in between) I find it so interesting that these disorders fall somewhere on a spectrum in relation to each other and it's not as black and white as they've been portrayed in mainstream media. There's a lot of overlap in medication and treatment because psychotic disorders affect the brain in similar ways even though there are key differences in each disorder. I've looked for videos and hardly any have covered this topic - the ones that have are just as confusing as the subject itself. I think it would be great to shed some light on a subject that seems so foreign and scary to most people! Thank you.

  44. Randy Ross
    Randy Ross
    Muaj më parë

    You are Nutz, you barely need any Lithium! It works for people for like one month, than they already have all the Lithium they need for the next couple decades! I knew a kid on Lithium, and it was no Good for Him! And no one should be all Drugged Up like that so they are acceptable to your Standards, and I say your Standards! Because clearly you have it out for Bi-Polar People! I dissent completely, and I seen way to many kids drugged out of their minds growing up because they didn't meet women of your age's standards! Why don't you put your money where your mouth is an go take a whole bunch of Lithium, years worth a day! And see how much that Fries your Brain your Freaken Moron! Oh and the Stigma Around Bi-Polar you say, what you are creating! As you Petrified anyone with any issues that some Cow like you wants them Drugged Up Out of their Minds!!!!

  45. Penelope hunter
    Penelope hunter
    Muaj më parë

    Yes.. and medication used to treat disorders like this “anti psychotics” can also cause a stroke.. which I didn’t know until I had one and I was explained this can cause it, to being told I was not to take antipsychotic medication again.

  46. Ruth Brent
    Ruth Brent
    Muaj më parë

    Don't give Lithium to 5 year olds.

  47. Frieda, Prinzessin von Anstalt
    Frieda, Prinzessin von Anstalt
    Muaj më parë

    There is a another type of BD called atypical BD. People with this type have most of their time (ultra(radian)) rapid cycling instead the classic episodes

  48. Rainbow Kitten
    Rainbow Kitten
    Muaj më parë

    Hello there fellow nirvana fans 😛

  49. Zetsuke4
    Zetsuke4
    Muaj më parë

    y

  50. Methane Gummybear
    Methane Gummybear
    Muaj më parë

    Finally, a video explaining why lithium works for bipolar disorder without being boring as hell! 😄

  51. Monica Inguanzo
    Monica Inguanzo
    Muaj më parë

    👍

  52. Simke sims
    Simke sims
    Muaj më parë

    I have couple of question for people dealing with bipolar disorder if you don't mind answering- When in manic episode, do you get angry or sad ever? And do you remember what you have had an argument about 10 minutes ago? How did you realise that you have a problem? And in depressive state, do you remember things you have said, done? I'm trying to understand because it seems to me that my friend has bipolar, she posts random friends on her ig stories, texted a married guy 400 messages, in the next moment she talks about the guy she is in a relationship with (they are not, they haven't spoken at all), she doesn't sleep, doesn't realise she has a problem. She started yelling at me for telling her that today is monday, because she is convinced it is sunday, it creeped me out. I just want to learn how to talk to her in that situations, and understand the disorder in order to help her, and me, because it started affecting my daily life. I feel scared and think constantly about her.

  53. SinkingSail
    SinkingSail
    Muaj më parë

    Oh oh, make one about Lamotrigine!

  54. Miguel Martinez
    Miguel Martinez
    Muaj më parë

    Soo what source were they citing that said GPCRs bind Na ?

  55. Prax Zimmerman
    Prax Zimmerman
    Muaj më parë

    Is it lithium carbonate in particular that's good, or just lithium ions in general? Like, would lithium chloride or lithium citrate be just as effective?

    1. Being Better
      Being Better
      4 ditë më parë

      I take lithium orotate everyday and it is more effective than lithium carbonate I think.

  56. William McGhee
    William McGhee
    Muaj më parë

    I've seen Lithium carbonate via injection transform a screaming, scary woman into a lady that could work all day in a kindergarden. Amazing stuff, for some people who struggle with periodic mental illness.

  57. Bean Dar
    Bean Dar
    Muaj më parë

    Lithium caused intense brain fog for me, lots of bad side effects I wish they would of went over in this video

  58. GeorgeNoiseless
    GeorgeNoiseless
    Muaj më parë

    How about also delving into C13H9NOSe, Ebselen as potentially safer alternative to Lithium? As a bonus it has potential anti-CoV activity. (Perhaps that in particular makes it too touchy a subject?)

  59. Ankit Mittal
    Ankit Mittal
    Muaj më parë

    So old mystery has gone solved at an extent. I figured it out that what it actually was. I was always obssesd with making movies in my mind with many things as like songs, special effects and actions scenes. One day an idea clicked in my mind that why should not i form a charcter. Who can express the imformation in a better way. Because how our mind understand anything. It is actually it's expression towards that thing. It is as like a field express towards an information itself and mould it into an another way. But the field transform itself by different patterns of concepts and information in our minds. Sane here i was expressing these character as like someone is doing a talk show and a teacher is teaching in classroom. And one day i got an idea about how a charcter can a desgined in a thiniking state. So i made them like that. And one day i got an idea to do something even beyond it. I realized that actually i am thinking by my mind but pretend to be an another mind. So why i can not make stories by that minds. So every idea came with a question for next possibility. So i was studying organic chemistry. And after looking at benzene ring i got an another crazy idea. It was an idea for something beyond the thinking mind. I thought that every charcter and mind has an inspiration. Just as like i watched a movie and i got an idea related with it. It can associations and dissociations of many already preexisting ideas. So what equations are going in an unconscious mind. No body can tell actually. So after looking at benzene ring i got an idea of a thinking box. I named it as imagination box. And it was next level of a thinking mind of a charcter. So i imagined something beyond the mind according to my concepts of mind. But it was just an another dimension of creative realm. So i formatted the concept of rotation. That every movement has significance and indication. And when a box rotates then it will indicates some random ideas related to formulated concept about it. And this is how actually our intellegence and conciousness works that way. Because i was expressing the process of idealization and cogintive mechanics into the form of a hypothetical model. Which crosses my already preexisting believes and faith about many things. And i challenged every idea and concept at a complete unique and strange level into the another realm. It is too much like science fiction.

  60. Emil
    Emil
    Muaj më parë

    I like this presenter.

  61. Ashleen Romano
    Ashleen Romano
    Muaj më parë

    Thank you for spreading awareness on bipolar disorder. My mum also has bipolar disorder & has been taking lithium for decades, it's the only thing that works for her. So it's interesting to learn more about & it's effectiveness on the brain.

  62. Vuovdi
    Vuovdi
    Muaj më parë

    the only time i was attacked by someone they were on lithium

  63. Elena
    Elena
    Muaj më parë

    Lithium to stabilize Mg levels? Umm, wouldn't an Mg supplement do that?

  64. justin blake
    justin blake
    Muaj më parë

    Lithium=poison Lithium=medicine Hmmm guess it depends wether ya making meth or meds

  65. Ellenor Bjornsdottir
    Ellenor Bjornsdottir
    Muaj më parë

    now do spironolactone, case series presented by Juruena in 2008.

  66. About Time
    About Time
    Muaj më parë

    As someone diagnosed with bipolar disorder, I truly appreciate your efforts in the video :)

  67. Whyntir
    Whyntir
    Muaj më parë

    I was on lithium and it gave me a feeling of not being real. Like my body and mind were disconnected. But I would probably try it again, ngl

    1. Naomi Lasby
      Naomi Lasby
      Muaj më parë

      Yessss my lithium/seroquel cocktail gave me EXACTLY that feeling, although helpful as treatment at the time

  68. Big Emu
    Big Emu
    Muaj më parë

    I was offered a choice between Lithium and Quetiapine, I chose the latter but It seems the main Ingredient of Quetiapine is Titanium Dioxide, how on earth does that factor into the treatment of Bipolar?

  69. ReineDeLaSeine14
    ReineDeLaSeine14
    Muaj më parë

    I was diagnosed in 2008 and I’ve never had to take lithium. Kind of mind blowing.

  70. ALEX CIOCCA
    ALEX CIOCCA
    Muaj më parë

    I believe it was originally in 7 up

  71. Lil Toker
    Lil Toker
    Muaj më parë

    No thanks! I'll just stick to crystal meth.

  72. Mind's Eye
    Mind's Eye
    Muaj më parë

    Easy answer. It doesn’t. It’s highly toxic. Destroys the liver and causes dementia.

  73. James Rendek
    James Rendek
    Muaj më parë

    Like a lobotomy, it quells the mind.

  74. ejonesss
    ejonesss
    Muaj më parë

    since lithium kicks sodium can it chase sodium out of the body? can the same anti depressant drug be used to treat hypernatremia by repelling the sodium out of the body?

    1. Taylor White
      Taylor White
      Muaj më parë

      It'll poison you before it gets to that point, being on lithium also means needing regular blood tests to make sure you don't spontaneously die

  75. Outsider
    Outsider
    Muaj më parë

    I just gor prescribed this a week ago. Thanks for the info!

  76. Drizzt
    Drizzt
    Muaj më parë

    I wonder what else had those doctors tried.

  77. Geovanni D.
    Geovanni D.
    Muaj më parë

    Lol this video makes lithium sound like a herbal medicine. It's not good for the brain, it turns you into a zombie by deactivating parts of your brains function. Get real.

  78. F L
    F L
    Muaj më parë

    it just dumbs you down it forces you be a zombie version of yourself.

  79. sunniesH
    sunniesH
    Muaj më parë

    Yes!

  80. TheOtherWay
    TheOtherWay
    Muaj më parë

    The mindfulness book "30 Days to Reduce Depression" by Harper Daniels is a good resource.

  81. samuel jordan
    samuel jordan
    Muaj më parë

    I’ve struggled with bi polar my whole life. I might try this. I’ve been off meds for years due to a cocktail of psych drugs I took as a kid that made my mental health worse. I wish their was a quick fix.

    1. Moheeb Saad
      Moheeb Saad
      22 ditë më parë

      Bipolar disorder caused by herpes viruses, try acyclovir

  82. Caleb Roseboom
    Caleb Roseboom
    Muaj më parë

    Lithium Carbonate does not cross the blood brain barrier! This is why it is ineffective and why many patients are given 50 to 100 times, a toxic dose, needed to be helpful. Orotic acid is a substance in mothers milk, when bound to this molecule, the supplement is called Lithium Orotate. Dr. john gray found this out and I am shocked that lithium Carbonate is being promoted here.

  83. Elizabeth Darsey
    Elizabeth Darsey
    Muaj më parë

    I’m 45, live in Georgia and since I was 15 I’ve personally experienced various issues that would fall under mental illness. Stranger still is the high number of relatives, both immediate and extended, who developed various issues of mental illness or diseases of the brain. Most people wouldn’t hear that and think anything of it....until I list out just how many relatives are included. It becomes even stranger when I explain how it impacts both my mother and father’s sides of my family. There are only two aspects that are shared across the board for both sides: 1. The high number who either were active duty military or were on bases as civil servants. 2. Everyone either lived in or spent extended periods in one town or rather in about a 30 mile radius of one town. To me the oddity is how/when people started having symptoms. As I said, mine started when I was 15 +/-, but my grandmothers both experienced their issues in the early part of 1990’s. That just happens to be the same general time frame as I was born in 75. I honestly think if I had a crystal ball or time travel machine and could go into the future 50-100 years, I would see that people have since discovered some major issue that sparked so many of these illnesses involving the brain/mind. What that common strand is, I haven’t a clue! I have contacted so many doctors, researchers, biologists, chemists, etc asking if they’re aware of any situation where such a wide spectrum of people would have such varied pathologies of the brain but who lived such different lifestyles. The answer so far as been the same... it doesn’t seem ‘natural’ but they can’t explain it either. The illnesses do go far and wide... Alzheimer’s, Parkinson’s, Benign brain tumors, GBM (brain cancer), Oligodendroglioma (brain cancer), strokes, aneurysm, bipolar disorder, major depression, substance abuse -alcohol, substance abuse - street drugs, substance abuse - prescription medications, insomnia, hallucinations (audible and visual), seizures, seizures, seizures. Anxiety disorders. My relatives have taken part in three large trial treatments: The medication Temodar for brain cancer; the medication RU486 for brain tumors (it’s otherwise known as abortion pill), and the GammaKnife trials again for brain tumors. As for the lithium, the video caught my attention because I will explain to people in a very sarcastic (albeit honest) manner that I think I’ve been on damn near every medication possible for mental illness with the exception of lithium, and I just have a fundamental issue being turned into a living, human version of the Energizer Bunny!! But I’ve had such horrible experiences with the medications I won’t chance Lithium. SSRIs, antidepressants, mood stabilizers, antipsychotics, anti anxiety, tranquilizers. It was ridiculous! And the only one that ever had a positive impact was the SSRI Celexa (citalopram) when I was a teenager. They weaned me off, issues came back and when they started it again, it was the beginning of a 20 year nightmare! It’s hard enough to fight the demons that come with mental illness, but when the suffering is increased exponentially because of the “treatment”, it’s a recipe for disaster! Maybe as they learn more about these drugs it will give them a reverse view onto the root cause of these illnesses and diseases!

    1. Moheeb Saad
      Moheeb Saad
      22 ditë më parë

      Bipolar disorder caused by herpes, try acyclovir

  84. Yuuga U
    Yuuga U
    Muaj më parë

    This stuff is poison! I was put on this and my symptoms got worse and I was puking stomach bile everyday... got to the point to where I was peeing blood

  85. MindEnhancement1.618
    MindEnhancement1.618
    Muaj më parë

    It works by lowering dopamine and glutamate and it increases GABA and serotonin. it also up regulates Tkrb the Brain-derived neurotrophic factor(Bdnf) receptor commonly called miracle gro for the brain. It also increase the amount of neurons in the prefrontal cortex, hippocampus and amygdala. It also reduces oxidative stress commonly thought to be a trigger of mania. It inhibits glycogen synthase kinase Lithium is neuroprotective, it lowers thyroid function, it protects against mitochondrial dysfunction, it decrease lipid peroxidation levels, it enhances cyclic adenosine monophosphate. Is an amazing element for the brain and body I disagree with the doses used in BPD though.

  86. Wombat.
    Wombat.
    2 muaj më parë

    How did anyone ever work out that eating *those* rocks would help mental distress????

  87. Esra Erimez
    Esra Erimez
    2 muaj më parë

    I think that body shaming Brit is terrible. You all should be ashamed of yourselves

    1. IdeaDriven
      IdeaDriven
      Muaj më parë

      Haven't met a single comment here doing it, definitely not top 50 xd

  88. Fuze
    Fuze
    2 muaj më parë

    protip for people with bipolar disorder that wanna save money on medicin: just chew on some batteries

  89. ronkirk50
    ronkirk50
    2 muaj më parë

    It is interesting to learn how these medications which were discovered by happen stance actually work in the body. Amazing advances are being made in molecular biology to the benefit of all mankind.

  90. Kaliland
    Kaliland
    2 muaj më parë

    Sodium out here being like “Na”

  91. Cris OG
    Cris OG
    2 muaj më parë

    I wonder how they came up with lithium as a medicine in the first place. "My son has the habit of licking batteries and now he is behaving much better. I wonder if lithium salts can be used as treatment..."

  92. june silverman b
    june silverman b
    2 muaj më parë

    Lithium (from Greek: λίθος, romanized: lithos, lit. 'stone') is a chemical element with the symbol Li and atomic number 3. It is a soft, silvery-white alkali metal. Under standard conditions, it is the lightest metal and the lightest solid element. Like all alkali metals, lithium is highly reactive and flammable, and must be stored in mineral oil. When cut, it exhibits a metallic luster, but moist air corrodes it quickly to a dull silvery gray, then black tarnish. It never occurs freely in nature, but only in (usually ionic) compounds, such as pegmatitic minerals, which were once the main source of lithium. Due to its solubility as an ion, it is present in ocean water and is commonly obtained from brines. Lithium metal is isolated electrolytically from a mixture of lithium chloride and potassium chloride.

  93. Heather Flanagan Anger
    Heather Flanagan Anger
    2 muaj më parë

    Lithium was disastrous for my husband”s bipolar disorder. It almost ruined our lives. NO ONE should ever be on that poison.

    1. Moheeb Saad
      Moheeb Saad
      22 ditë më parë

      Bipolar disorder caused by herpes viruses, try acyclovir + zinc

    2. Nina J
      Nina J
      Muaj më parë

      @Henk - Yeah, but 80% of them get a lifelong, very uncomfortable condition called hypothyroidism, but no one mentions it ever... Some force you to take it and shame you for resisting, while others say it's poison.

    3. Henk -
      Henk -
      2 muaj më parë

      people react different to drugs. I'm sorry it was so disastrous for you and your family. But that doesn't mean it doesn't work for other people.

  94. DsXB
    DsXB
    2 muaj më parë

    That power pose at 2:30 tho

  95. Connor McLaughlin
    Connor McLaughlin
    2 muaj më parë

    me, a bipolar 2, possibly at the start of a hypomanic episode on 200mg lamotrigine & 300mg lithium 👁👄👁

    1. IdeaDriven
      IdeaDriven
      Muaj më parë

      If you'll ever meet toxicity problems with lithium, try lithium orotate. Lamictal didn't work for me, then I remembered I saw a video where a guy said he used some supplies to treat BP, so I researched, read Amazon reviews and tried. Completely removed any depression or hypimania

  96. 7Risen7Phoenix7
    7Risen7Phoenix7
    2 muaj më parë

    I've been on lithium and many other medications for ten years since my last, and hopefully final, hospitalization, and I've never felt better.

  97. David Provencher
    David Provencher
    2 muaj më parë

    Now I need to listen to the Nirvana song again.

  98. Miss Clark
    Miss Clark
    2 muaj më parë

    Didn't mention about the rotting your teeth. It helps but I would have rather had ECT over taking Lithium and the 8 other psych meds prescribed for me.

  99. edward lewis
    edward lewis
    2 muaj më parë

    @0:51 "over the next 70 years, this compound, which we'll just call "lithium" from now on, " @1:30 "so having a drug like lithium is incredibly important" 1: describing lithium as a drug is an extremely poor description. 2: having wasted words explaining that you are going to use the word "lithium" instead of saying "lithium carbonate" is an extremely poor excuse for making the subsequent misstatements; it would have been better to just say "lithium carbonate" 3: even describing lithium carbonate as a drug is wierd; that's like describing ordinary table salt as a drug

  100. Dawn Smith
    Dawn Smith
    2 muaj më parë

    This lady sounds dumb too excited with little good information.